miRNA control of tumor cell invasion and metastasis

MicroRNAs have emerged as a novel class of noncoding RNAs that regulate gene expression at the post‐translational level in almost every biological event. A large body of evidence indicates that microRNAs regulate the expression of different genes that play an important role in cancer cell invasion,...

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Veröffentlicht in:International journal of cancer 2010-03, Vol.126 (6), p.1283-1290
Hauptverfasser: Baranwal, Somesh, Alahari, Suresh K.
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container_title International journal of cancer
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creator Baranwal, Somesh
Alahari, Suresh K.
description MicroRNAs have emerged as a novel class of noncoding RNAs that regulate gene expression at the post‐translational level in almost every biological event. A large body of evidence indicates that microRNAs regulate the expression of different genes that play an important role in cancer cell invasion, migration and metastasis. In this review, we briefly describe the role of various miRNAs in invasion, migration and metastasis which are essential steps during cancer progression.
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subjects Animals
Biological and medical sciences
Biomarkers, Tumor - genetics
epithelial‐mesenchymal transition
Gene Expression Regulation, Neoplastic
Humans
invasion
Medical sciences
metastasis suppressor
MicroRNAs - genetics
miRNA
Models, Biological
Neoplasm Invasiveness
Neoplasm Metastasis
Neoplasms - genetics
Neoplasms - pathology
Tumor Suppressor Proteins - genetics
Tumors
title miRNA control of tumor cell invasion and metastasis
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