miRNA control of tumor cell invasion and metastasis

MicroRNAs have emerged as a novel class of noncoding RNAs that regulate gene expression at the post‐translational level in almost every biological event. A large body of evidence indicates that microRNAs regulate the expression of different genes that play an important role in cancer cell invasion,...

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Veröffentlicht in:	International journal of cancer 2010-03, Vol.126 (6), p.1283-1290
Hauptverfasser:	Baranwal, Somesh, Alahari, Suresh K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biomarkers, Tumor - genetics epithelial‐mesenchymal transition Gene Expression Regulation, Neoplastic Humans invasion Medical sciences metastasis suppressor MicroRNAs - genetics miRNA Models, Biological Neoplasm Invasiveness Neoplasm Metastasis Neoplasms - genetics Neoplasms - pathology Tumor Suppressor Proteins - genetics Tumors
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Beschreibung
Zusammenfassung:	MicroRNAs have emerged as a novel class of noncoding RNAs that regulate gene expression at the post‐translational level in almost every biological event. A large body of evidence indicates that microRNAs regulate the expression of different genes that play an important role in cancer cell invasion, migration and metastasis. In this review, we briefly describe the role of various miRNAs in invasion, migration and metastasis which are essential steps during cancer progression.
ISSN:	0020-7136 1097-0215
DOI:	10.1002/ijc.25014