A Marker of Endotoxemia Is Associated With Obesity and Related Metabolic Disorders in Apparently Healthy Chinese

Elevated lipopolysaccharide-binding protein (LBP), a marker of subclinical endotoxemia, may be involved in the pathogenesis of obesity and metabolic risk. We aimed to investigate the association between plasma LBP and metabolic disorders in apparently healthy Chinese. A population-based study includ...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Diabetes care 2010-09, Vol.33 (9), p.1925-1932
Hauptverfasser:	LIANG SUN, ZHIJIE YU, HU, Frank B, XU LIN, XINGWANG YE, SHURONG ZOU, HUAIXING LI, DANXIA YU, HONGYU WU, YAN CHEN, DORE, Joel, CLEMENT, Karine
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute-Phase Proteins Adiponectin - blood Adult Asians Biological and medical sciences C-Reactive Protein - metabolism Cardiovascular disease Carrier Proteins - blood Cholesterol Diabetes Mellitus, Type 2 - blood Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Endotoxemia - blood Enzyme-Linked Immunosorbent Assay Female Humans Insulin resistance Interleukin-6 - blood Leptin - blood Male Medical research Medical sciences Medicine, Experimental Membrane Glycoproteins - blood Metabolic diseases Metabolic disorders Metabolic Syndrome - blood Middle Aged Miscellaneous Obesity Obesity - blood Original Research Public health. Hygiene Public health. Hygiene-occupational medicine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Elevated lipopolysaccharide-binding protein (LBP), a marker of subclinical endotoxemia, may be involved in the pathogenesis of obesity and metabolic risk. We aimed to investigate the association between plasma LBP and metabolic disorders in apparently healthy Chinese. A population-based study including 559 overweight/obese (BMI >or=24.0 kg/m(2)) and 500 normal-weight (18.0
ISSN:	0149-5992 1935-5548
DOI:	10.2337/dc10-0340