Effect of Allopurinol in Chronic Kidney Disease Progression and Cardiovascular Risk

Hyperuricemia is associated with hypertension, inflammation, renal disease progression, and cardiovascular disease. However, no data are available regarding the effect of allopurinol in patients with chronic kidney disease. We conducted a prospective, randomized trial of 113 patients with estimated...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical journal of the American Society of Nephrology 2010-08, Vol.5 (8), p.1388-1393
Hauptverfasser:	Goicoechea, Marian, de Vinuesa, Soledad García, Verdalles, Ursula, Ruiz-Caro, Caridad, Ampuero, Jara, Rincón, Abraham, Arroyo, David, Luño, José
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Allopurinol - adverse effects Allopurinol - therapeutic use Biomarkers - blood C-Reactive Protein - metabolism Cardiovascular Diseases - blood Cardiovascular Diseases - etiology Cardiovascular Diseases - prevention & control Chi-Square Distribution Chronic Disease Disease Progression Glomerular Filtration Rate - drug effects Gout Suppressants - adverse effects Gout Suppressants - therapeutic use Hospitalization Humans Hyperuricemia - blood Hyperuricemia - etiology Hyperuricemia - prevention & control Inflammation Mediators - blood Kaplan-Meier Estimate Kidney Diseases - blood Kidney Diseases - complications Kidney Diseases - drug therapy Kidney Diseases - physiopathology Middle Aged Original Proportional Hazards Models Prospective Studies Risk Assessment Risk Factors Spain Time Factors Treatment Outcome Uric Acid - blood
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Hyperuricemia is associated with hypertension, inflammation, renal disease progression, and cardiovascular disease. However, no data are available regarding the effect of allopurinol in patients with chronic kidney disease. We conducted a prospective, randomized trial of 113 patients with estimated GFR (eGFR)
ISSN:	1555-9041 1555-905X
DOI:	10.2215/CJN.01580210