impact of Schiff bases on antibiotic production by Streptomyces hygroscopicus

A media consisting of isatin-Schiff bases (isatin-3-thiosemicarbazone, isatin-3-semicarbazone, and isatin-3-phenylhydrazone) was developed to maximize the production of antibiotics Hexaene H-85 and Azalomycine B by Streptomyces hygroscopicus. The media isatin-3-thiosemicarbazone resulted in the maxi...

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Veröffentlicht in:Medicinal chemistry research 2010-09, Vol.19 (7), p.690-697
Hauptverfasser: Ilić, Slavica B, Konstantinović, Sandra S, Savić, Dragiša S, Veljković, Vlada B, Gojgić-Cvijović, G
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container_end_page 697
container_issue 7
container_start_page 690
container_title Medicinal chemistry research
container_volume 19
creator Ilić, Slavica B
Konstantinović, Sandra S
Savić, Dragiša S
Veljković, Vlada B
Gojgić-Cvijović, G
description A media consisting of isatin-Schiff bases (isatin-3-thiosemicarbazone, isatin-3-semicarbazone, and isatin-3-phenylhydrazone) was developed to maximize the production of antibiotics Hexaene H-85 and Azalomycine B by Streptomyces hygroscopicus. The media isatin-3-thiosemicarbazone resulted in the maximum antibiotics concentration of 372 μg cm⁻³ for Hexaene H-85 and 118 μg cm⁻³ for Azalomycine B. The impact of modified media on soil morphology also was investigated.
doi_str_mv 10.1007/s00044-009-9223-7
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subjects anatomy and morphology
Antibiotic production
Biochemistry
Biomedical and Life Sciences
Biomedicine
Cell Biology
Original Research
Pharmacology/Toxicology
Schiff base
Streptomyces hygroscopicus
title impact of Schiff bases on antibiotic production by Streptomyces hygroscopicus
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