Secondary fibrosarcoma of the brain stem treated with cyclophosphamide and Imatinib
Radiation-induced midbrain fibrosarcoma is a rare, highly aggressive tumor, which is associated with poor prognosis. We present the case of a 48-year old man with brainstem fibrosarcoma 20 years following radiation therapy received for a pituitary tumor. We discuss this case in the context of the di...
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| Veröffentlicht in: | Journal of neuro-oncology 2010-08, Vol.99 (1), p.123-128 |
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| container_title | Journal of neuro-oncology |
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| creator | Alexandru, Daniela Van Horn, Denise K. Bota, Daniela Annenelie |
| description | Radiation-induced midbrain fibrosarcoma is a rare, highly aggressive tumor, which is associated with poor prognosis. We present the case of a 48-year old man with brainstem fibrosarcoma 20 years following radiation therapy received for a pituitary tumor. We discuss this case in the context of the diagnostic criteria for these tumors, and previous reports of secondary and primary sarcomas of the central nervous system. |
| doi_str_mv | 10.1007/s11060-009-0096-x |
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We present the case of a 48-year old man with brainstem fibrosarcoma 20 years following radiation therapy received for a pituitary tumor. 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| ispartof | Journal of neuro-oncology, 2010-08, Vol.99 (1), p.123-128 |
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| language | eng |
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| source | MEDLINE; SpringerNature Journals |
| subjects | Antineoplastic Agents - therapeutic use Benzamides Brain Stem Neoplasms - drug therapy Brain Stem Neoplasms - pathology Brain Stem Neoplasms - secondary Case Report Cyclophosphamide - therapeutic use Fibrosarcoma - drug therapy Fibrosarcoma - pathology Fibrosarcoma - secondary Glial Fibrillary Acidic Protein - metabolism Humans Imatinib Mesylate Magnetic Resonance Imaging - methods Male Medicine Medicine & Public Health Mesencephalon - pathology Middle Aged Neurology Oncology Piperazines - therapeutic use Pyrimidines - therapeutic use S100 Proteins - metabolism |
| title | Secondary fibrosarcoma of the brain stem treated with cyclophosphamide and Imatinib |
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