Secondary fibrosarcoma of the brain stem treated with cyclophosphamide and Imatinib

Radiation-induced midbrain fibrosarcoma is a rare, highly aggressive tumor, which is associated with poor prognosis. We present the case of a 48-year old man with brainstem fibrosarcoma 20 years following radiation therapy received for a pituitary tumor. We discuss this case in the context of the di...

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Veröffentlicht in:Journal of neuro-oncology 2010-08, Vol.99 (1), p.123-128
Hauptverfasser: Alexandru, Daniela, Van Horn, Denise K., Bota, Daniela Annenelie
Format: Artikel
Sprache:eng
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Zusammenfassung:Radiation-induced midbrain fibrosarcoma is a rare, highly aggressive tumor, which is associated with poor prognosis. We present the case of a 48-year old man with brainstem fibrosarcoma 20 years following radiation therapy received for a pituitary tumor. We discuss this case in the context of the diagnostic criteria for these tumors, and previous reports of secondary and primary sarcomas of the central nervous system.
ISSN:0167-594X
1573-7373
DOI:10.1007/s11060-009-0096-x