Zinc Cream and Reliability of Tuberculosis Skin Testing

Zinc Cream and Reliability of Tuberculosis Skin Testing

In 50 healthy Peruvian shantytown residents, zinc cream applied to tuberculosis skin-test sitescaused a 32% increase in induration compared with placebo cream. Persons with lower plasma zinc had smaller skin-test reactions and greater augmentation with zinc cream. Zinc deficiency caused false-negati...

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Veröffentlicht in:Emerging infectious diseases 2007-07, Vol.13 (7), p.1101-1104
Hauptverfasser: Rao, V. Bhargavi, Pelly, Tom F., Gilman, Robert H., Cabrera, Lilia, Delgado, Jose, Soto, Giselle, Friedland, Jon S., Escombe, A. Roderick, Black, Robert E., Evans, Carlton A.
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Sprache:eng
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Zusammenfassung:In 50 healthy Peruvian shantytown residents, zinc cream applied to tuberculosis skin-test sitescaused a 32% increase in induration compared with placebo cream. Persons with lower plasma zinc had smaller skin-test reactions and greater augmentation with zinc cream. Zinc deficiency caused false-negative skin-test results, and topical zinc supplementation augmented antimycobacterial immune responses enough to improve diagnosis.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid1307.070227