Clinicopathologic significance of slug expression in human intrahepatic cholangiocarcinoma

AIM:To explore the expression and function of slug,a transcriptional repressor,in human intrahepatic cholangiocarcinoma(IHCC)and identify its role in IHCC progression.METHODS:Expression of slug was detected in 36 cases of IHCC and 12 cases of normal intrahepatic bile ducts and liver parenchyma by im...

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Veröffentlicht in:World journal of gastroenterology : WJG 2010-05, Vol.16 (20), p.2554-2557
Hauptverfasser: Zhang, Ke-Jun, Zhang, Bing-Yuan, Zhang, Kun-Peng, Tang, Li-Min, Liu, Shi-Song, Zhu, Dong-Ming, Zhang, Dian-Liang
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container_end_page 2557
container_issue 20
container_start_page 2554
container_title World journal of gastroenterology : WJG
container_volume 16
creator Zhang, Ke-Jun
Zhang, Bing-Yuan
Zhang, Kun-Peng
Tang, Li-Min
Liu, Shi-Song
Zhu, Dong-Ming
Zhang, Dian-Liang
description AIM:To explore the expression and function of slug,a transcriptional repressor,in human intrahepatic cholangiocarcinoma(IHCC)and identify its role in IHCC progression.METHODS:Expression of slug was detected in 36 cases of IHCC and 12 cases of normal intrahepatic bile ducts and liver parenchyma by immunohistochemistry.The patients were divided into low slug expression group(< 20%of carcinoma cells stained)and high slug expression group(≥20%of carcinoma cells stained).Slug expression was correlated with clini...
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source MEDLINE; Baishideng "World Journal of" online journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection
subjects Adult
Aged
Bile Duct Neoplasms - diagnosis
Bile Duct Neoplasms - metabolism
Bile Duct Neoplasms - pathology
Bile Ducts, Intrahepatic - metabolism
Bile Ducts, Intrahepatic - pathology
Biomarkers, Tumor - metabolism
Brief
Cholangiocarcinoma - diagnosis
Cholangiocarcinoma - metabolism
Cholangiocarcinoma - pathology
Disease Progression
Female
Humans
Lymphatic Metastasis - pathology
Male
Middle Aged
Prognosis
Snail Family Transcription Factors
Survival Rate
Transcription Factors - metabolism
title Clinicopathologic significance of slug expression in human intrahepatic cholangiocarcinoma
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