Herbal extracts as hepatoprotectants against acetaminophen hepatotoxicity
Many plant-derived natural products have the potential to be hepatoprotective and therefore can be used to treat acute and chronic liver diseases. The challenge is to identify the most promising compounds and evaluate their protective mechanism. In a recently published article, Wang et al evaluated...
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| Veröffentlicht in: | World journal of gastroenterology : WJG 2010-05, Vol.16 (19), p.2448-2450 |
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| container_title | World journal of gastroenterology : WJG |
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| creator | Jaeschke, Hartmut Williams, C David McGill, Mitchell R Farhood, Anwar |
| description | Many plant-derived natural products have the potential to be hepatoprotective and therefore can be used to treat acute and chronic liver diseases. The challenge is to identify the most promising compounds and evaluate their protective mechanism. In a recently published article, Wang et al evaluated extracts of the plant Gentiana manshurica Kitagawa (GM) in a model of acetaminophen hepatotoxicity. The authors concluded that GM is hepatoprotective against acetaminopheninduced liver injury due to its antioxida... |
| doi_str_mv | 10.3748/wjg.v16.i19.2448 |
| format | Article |
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The challenge is to identify the most promising compounds and evaluate their protective mechanism. In a recently published article, Wang et al evaluated extracts of the plant Gentiana manshurica Kitagawa (GM) in a model of acetaminophen hepatotoxicity. 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The challenge is to identify the most promising compounds and evaluate their protective mechanism. In a recently published article, Wang et al evaluated extracts of the plant Gentiana manshurica Kitagawa (GM) in a model of acetaminophen hepatotoxicity. 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| issn | 1007-9327 2219-2840 |
| language | eng |
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| source | MEDLINE; Baishideng "World Journal of" online journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Acetaminophen Animals Antioxidants - pharmacology Apoptosis - drug effects Chemical and Drug Induced Liver Injury - etiology Chemical and Drug Induced Liver Injury - pathology Chemical and Drug Induced Liver Injury - prevention & control Cytoprotection Disease Models, Animal Gentiana Letters To The Editor Liver - drug effects Liver - pathology Mice Oxidative Stress - drug effects Plant Extracts - pharmacology |
| title | Herbal extracts as hepatoprotectants against acetaminophen hepatotoxicity |
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