Herbal extracts as hepatoprotectants against acetaminophen hepatotoxicity

Many plant-derived natural products have the potential to be hepatoprotective and therefore can be used to treat acute and chronic liver diseases. The challenge is to identify the most promising compounds and evaluate their protective mechanism. In a recently published article, Wang et al evaluated...

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Veröffentlicht in:World journal of gastroenterology : WJG 2010-05, Vol.16 (19), p.2448-2450
Hauptverfasser: Jaeschke, Hartmut, Williams, C David, McGill, Mitchell R, Farhood, Anwar
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Sprache:eng
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Zusammenfassung:Many plant-derived natural products have the potential to be hepatoprotective and therefore can be used to treat acute and chronic liver diseases. The challenge is to identify the most promising compounds and evaluate their protective mechanism. In a recently published article, Wang et al evaluated extracts of the plant Gentiana manshurica Kitagawa (GM) in a model of acetaminophen hepatotoxicity. The authors concluded that GM is hepatoprotective against acetaminopheninduced liver injury due to its antioxida...
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v16.i19.2448