Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency: randomised placebo controlled trial

Objectives To study the effects of metformin on the incidence of vitamin B-12 deficiency (

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Bibliographische Detailangaben
Veröffentlicht in:	BMJ 2010-05, Vol.340 (7757), p.1177-1177
Hauptverfasser:	de Jager, Jolien, Kooy, Adriaan, Lehert, Philippe, Wulffelé, Michiel G, van der Kolk, Jan, Bets, Daniël, Verburg, Joop, Donker, Ab J M, Stehouwer, Coen D A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Clinical Trials (Epidemiology) Confidence intervals Diabetes Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - drug therapy Experimentation Family medical history Female Folic Acid - metabolism Health Education Health Promotion Homocysteine Homocysteine - metabolism Humans Hypoglycemic Agents - administration & dosage Hypoglycemic Agents - adverse effects Insulin Laboratories Long term Long-Term Care Male Metabolic Disorders Metformin - administration & dosage Metformin - adverse effects Middle Aged Mortality Placebos Risk Factors Scholarly publishing Smoking Smoking and Tobacco Studies Type 2 diabetes mellitus Vitamin B Vitamin B 12 - metabolism Vitamin B 12 Deficiency - chemically induced Vitamin B12 Vitamin deficiency
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Beschreibung
Zusammenfassung:	Objectives To study the effects of metformin on the incidence of vitamin B-12 deficiency (
ISSN:	0959-8138 1468-5833 1756-1833
DOI:	10.1136/bmj.c2181