Brown Fat and the Myth of Diet-Induced Thermogenesis

The notion that brown adipose tissue (BAT) in mice or humans maintains energy balance by burning off excess calories seems incompatible with evolutionary biology. Studies in obese rats and mice lacking UCP1 indicate that diet-induced thermogenesis by BAT is unlikely.

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Veröffentlicht in:Cell metabolism 2010-04, Vol.11 (4), p.263-267
1. Verfasser: Kozak, Leslie P.
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description The notion that brown adipose tissue (BAT) in mice or humans maintains energy balance by burning off excess calories seems incompatible with evolutionary biology. Studies in obese rats and mice lacking UCP1 indicate that diet-induced thermogenesis by BAT is unlikely.
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subjects Adaptation, Biological - physiology
Adipose Tissue, Brown - physiology
Animals
Diet
Energy Metabolism - physiology
Humans
Ion Channels - genetics
Ion Channels - metabolism
Mice
Mitochondrial Proteins - genetics
Mitochondrial Proteins - metabolism
Models, Biological
Rats
Thermogenesis - physiology
Uncoupling Protein 1
title Brown Fat and the Myth of Diet-Induced Thermogenesis
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