Brown Fat and the Myth of Diet-Induced Thermogenesis

The notion that brown adipose tissue (BAT) in mice or humans maintains energy balance by burning off excess calories seems incompatible with evolutionary biology. Studies in obese rats and mice lacking UCP1 indicate that diet-induced thermogenesis by BAT is unlikely.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cell metabolism 2010-04, Vol.11 (4), p.263-267
1. Verfasser:	Kozak, Leslie P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Biological - physiology Adipose Tissue, Brown - physiology Animals Diet Energy Metabolism - physiology Humans Ion Channels - genetics Ion Channels - metabolism Mice Mitochondrial Proteins - genetics Mitochondrial Proteins - metabolism Models, Biological Rats Thermogenesis - physiology Uncoupling Protein 1
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The notion that brown adipose tissue (BAT) in mice or humans maintains energy balance by burning off excess calories seems incompatible with evolutionary biology. Studies in obese rats and mice lacking UCP1 indicate that diet-induced thermogenesis by BAT is unlikely.
ISSN:	1550-4131 1932-7420
DOI:	10.1016/j.cmet.2010.03.009