Efficacy of atenolol and captopril in reducing risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 39

Abstract Objective: To determine whether tight control of blood pressure with either a β blocker or an angiotensin converting enzyme inhibitor has a specific advantage or disadvantage in preventing the macrovascular and microvascular complications of type 2 diabetes. Design: Randomised controlled tr...

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Veröffentlicht in:	BMJ 1998-09, Vol.317 (7160), p.713-720
1. Verfasser:	Group, UK Prospective Diabetes Study
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin converting enzyme inhibitors Antihypertensives Blood pressure Diabetes Diabetes complications Diabetic angiopathies Diabetic nephropathies Diuretics Enzymes Funding Heart attacks Heart failure Hypertension Mortality Myocardial infarction Studies Type 1 diabetes mellitus Type 2 diabetes mellitus
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Beschreibung
Zusammenfassung:	Abstract Objective: To determine whether tight control of blood pressure with either a β blocker or an angiotensin converting enzyme inhibitor has a specific advantage or disadvantage in preventing the macrovascular and microvascular complications of type 2 diabetes. Design: Randomised controlled trial comparing an angiotensin converting enzyme inhibitor (captopril) with a β blocker (atenolol) in patients with type 2 diabetes aiming at a blood pressure of
ISSN:	0959-8138 1468-5833 1756-1833
DOI:	10.1136/bmj.317.7160.713