The active management of risk in multiparous pregnancy at term: association between a higher preventive labor induction rate and improved birth outcomes

Objective To determine whether exposure of multiparous women to a high rate of preventive labor induction was associated with a significantly lower cesarean delivery rate. Study Design Retrospective cohort study involving 123 multiparous women, who were exposed to the frequent use of preventive labo...

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Veröffentlicht in:American journal of obstetrics and gynecology 2009-03, Vol.200 (3), p.250.e1-250.e13
Hauptverfasser: Nicholson, James M., MD, MSCE, Caughey, Aaron B., MD, PhD, Stenson, Morghan H., RN, BSN, SNM, Cronholm, Peter F., MD, MSCE, Kellar, Lisa, MD, Bennett, Ian, MD, PhD, Margo, Katie, MD, Straton, Joseph B., MD, MSCE
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Sprache:eng
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Zusammenfassung:Objective To determine whether exposure of multiparous women to a high rate of preventive labor induction was associated with a significantly lower cesarean delivery rate. Study Design Retrospective cohort study involving 123 multiparous women, who were exposed to the frequent use of preventive labor induction, and 304 multiparous women, who received standard management. Rates of cesarean delivery and other adverse birth outcomes were compared in the 2 groups. Logistic regression controlled for confounding covariates. Results The exposed group had a lower cesarean delivery rate (adjusted odds ratio, 0.09; 0.8% vs 9.9%; P = .02) and a higher uncomplicated vaginal delivery rate (odds ratio, 0.53; 78.9% vs 66.4%; P = .01). Exposure was not associated with higher rates of other adverse birth outcomes. Conclusion Exposure of multiparous women to a high rate of preventive labor induction was significantly associated with improved birth outcomes, including a very low cesarean delivery rate. A prospective randomized trial is needed to determine causality.
ISSN:0002-9378
1097-6868
DOI:10.1016/j.ajog.2008.08.053