Cryoglobulinaemic vasculitis: classification and clinical and therapeutic aspects

Cryoglobulinaemia may cause cutaneous vasculitis and glomerulonephritis, potentially leading to end stage renal failure. An important proportion of cryoglobulinaemias are secondary to hepatitis C virus infection. Emerging antiviral treatment options offer a chance for causal therapy of these cases o...

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Veröffentlicht in:	Postgraduate medical journal 2007-02, Vol.83 (976), p.87-94
Hauptverfasser:	Braun, Gerald S, Horster, Sophia, Wagner, Katrin S, Ihrler, Stephan, Schmid, Holger
Format:	Artikel
Sprache:	eng
Schlagworte:	ANCA antineutrophil cytoplasmic antibody Biological and medical sciences Cryoglobulinemia - classification Cryoglobulinemia - complications Cryoglobulinemia - therapy General aspects HBV HCV hepatitis B virus Hepatitis C virus Humans Kidney Diseases - etiology Medical sciences membranoproliferative glomerulonephritis MPGN Prognosis Review Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Vasculitis - classification Vasculitis - etiology Vasculitis - therapy
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Zusammenfassung:	Cryoglobulinaemia may cause cutaneous vasculitis and glomerulonephritis, potentially leading to end stage renal failure. An important proportion of cryoglobulinaemias are secondary to hepatitis C virus infection. Emerging antiviral treatment options offer a chance for causal therapy of these cases of cryoglobulinaemia. This review summarises the classification and clinical and therapeutic aspects of cryoglobulinaemic vasculitis and glomerulonephritis.
ISSN:	0032-5473 1469-0756
DOI:	10.1136/pgmj.2006.046078