A compiled and systematic reference map of nucleosome positions across the Saccharomyces cerevisiae genome

Nucleosomes have position-specific functions in controlling gene expression. A complete systematic genome-wide reference map of absolute and relative nucleosome positions is needed to minimize potential confusion when referring to the function of individual nucleosomes (or nucleosome-free regions) a...

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Veröffentlicht in:Genome Biology (Online Edition) 2009-01, Vol.10 (10), p.R109-2259
Hauptverfasser: Jiang, Cizhong, Pugh, B Franklin
Format: Artikel
Sprache:eng
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Zusammenfassung:Nucleosomes have position-specific functions in controlling gene expression. A complete systematic genome-wide reference map of absolute and relative nucleosome positions is needed to minimize potential confusion when referring to the function of individual nucleosomes (or nucleosome-free regions) across datasets. We compiled six high-resolution genome-wide maps of Saccharomyces cerevisiae nucleosome positions from multiple labs and detection platforms, and report new insights. Data downloads, reference position assignment software, queries, and a visualization browser are available online http://atlas.bx.psu.edu/.
ISSN:1474-760X
1465-6906
1474-760X
1465-6914
DOI:10.1186/gb-2009-10-10-r109