Effects of Long-Term Sildenafil Treatment for Pulmonary Hypertension in Infants with Chronic Lung Disease

Objective To determine the clinical course and outcomes of infants with chronic lung disease (CLD) and pulmonary hypertension (PH) who received prolonged sildenafil therapy. Study design We conducted a retrospective review of 25 patients

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Veröffentlicht in:	The Journal of pediatrics 2009-03, Vol.154 (3), p.379-384.e2
Hauptverfasser:	Mourani, Peter M., MD, Sontag, Marci K., PhD, Ivy, D. Dunbar, MD, Abman, Steven H., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blood Pressure - drug effects Bronchopulmonary Dysplasia - complications Echocardiography Female General aspects Hernias, Diaphragmatic, Congenital Humans Hypertension, Pulmonary - diagnosis Hypertension, Pulmonary - drug therapy Hypertension, Pulmonary - etiology Infant Infant, Newborn Infant, Premature Male Medical sciences Pediatrics Phosphodiesterase Inhibitors - administration & dosage Phosphodiesterase Inhibitors - adverse effects Piperazines - administration & dosage Piperazines - adverse effects Pneumology Pulmonary Artery - drug effects Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases Purines - administration & dosage Purines - adverse effects Retrospective Studies Sildenafil Citrate Sulfones - administration & dosage Sulfones - adverse effects Treatment Outcome
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Beschreibung
Zusammenfassung:	Objective To determine the clinical course and outcomes of infants with chronic lung disease (CLD) and pulmonary hypertension (PH) who received prolonged sildenafil therapy. Study design We conducted a retrospective review of 25 patients
ISSN:	0022-3476 1097-6833
DOI:	10.1016/j.jpeds.2008.09.021