Review of Peak Detection Algorithms in Liquid-Chromatography-Mass Spectrometry

Review of Peak Detection Algorithms in Liquid-Chromatography-Mass Spectrometry

In this review, we will discuss peak detection in Liquid-Chromatography-Mass Spectrometry (LC/MS) from a signal processing perspective. A brief introduction to LC/MS is followed by a description of the major processing steps in LC/MS. Specifically, the problem of peak detection is formulated and var...

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Veröffentlicht in:Current genomics 2009-09, Vol.10 (6), p.388-401
Hauptverfasser: Zhang, Jianqiu, Gonzalez, Elias, Hestilow, Travis, Haskins, William, Huang, Yufei
Format: Artikel
Sprache:eng
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Zusammenfassung:In this review, we will discuss peak detection in Liquid-Chromatography-Mass Spectrometry (LC/MS) from a signal processing perspective. A brief introduction to LC/MS is followed by a description of the major processing steps in LC/MS. Specifically, the problem of peak detection is formulated and various peak detection algorithms are described and compared.
ISSN:1389-2029
1875-5488
DOI:10.2174/138920209789177638