Monoclonal Antibodies with Orthogonal Azaspiracid Epitopes

Azaspiracid antibodies: Immunization of azaspiracid immunoconjugates has elicited monoclonal antibodies with distinct epitopes on the marine toxin; this will open the way toward azaspiracid diagnostics and the detection of contaminated shellfish before they can enter the food supply.

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Bibliographische Detailangaben
Veröffentlicht in:	Chembiochem : a European journal of chemical biology 2009-07, Vol.10 (10), p.1625-1629
Hauptverfasser:	Frederick, Michael O, De Lamo Marin, Sandra, Janda, Kim D, Nicolaou, K.C, Dickerson, Tobin J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals antibodies Antibodies, Monoclonal - chemistry Antibodies, Monoclonal - immunology Antibodies, Monoclonal - metabolism azaspiracid Enzyme-Linked Immunosorbent Assay Epitopes - chemistry Epitopes - metabolism immunoassays immunoconjugate Immunoconjugates - immunology Immunoconjugates - metabolism Marine Toxins - analysis Marine Toxins - chemistry Marine Toxins - immunology Mice Shellfish - toxicity Spiro Compounds - analysis Spiro Compounds - chemistry Spiro Compounds - immunology toxicity
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Beschreibung
Zusammenfassung:	Azaspiracid antibodies: Immunization of azaspiracid immunoconjugates has elicited monoclonal antibodies with distinct epitopes on the marine toxin; this will open the way toward azaspiracid diagnostics and the detection of contaminated shellfish before they can enter the food supply.
ISSN:	1439-4227 1439-7633
DOI:	10.1002/cbic.200900201