Two Cases of Mycobacterium microti-Induced Culture-Negative Tuberculosis

We present descriptions of two human Mycobacterium microti infections: one of a patient with pulmonary disease and one of a patient with osteomyelitis of the hip. Both patients had acid-fast bacilli and a positive Mycobacterium tuberculosis complex PCR from clinical specimens, but mycobacterial cult...

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Veröffentlicht in:	Journal of Clinical Microbiology 2009-09, Vol.47 (9), p.3038-3040
Hauptverfasser:	de Jong, Eefje, Rentenaar, Rob J, van Pelt, Rob, de Lange, Wiel, Schreurs, Wim, van Soolingen, Dick, Sturm, Patrick D.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteriology Biological and medical sciences Case Reports Fundamental and applied biological sciences. Psychology Hip - microbiology Humans Lung - microbiology Male Microbiology Middle Aged Miscellaneous Mycobacterium - classification Mycobacterium - isolation & purification Polymerase Chain Reaction - methods Tuberculosis, Osteoarticular - diagnosis Tuberculosis, Osteoarticular - microbiology Tuberculosis, Pulmonary - diagnosis Tuberculosis, Pulmonary - microbiology
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Beschreibung
Zusammenfassung:	We present descriptions of two human Mycobacterium microti infections: one of a patient with pulmonary disease and one of a patient with osteomyelitis of the hip. Both patients had acid-fast bacilli and a positive Mycobacterium tuberculosis complex PCR from clinical specimens, but mycobacterial cultures remained negative. The microbiological diagnosis was established by molecular methods.
ISSN:	0095-1137 1098-660X
DOI:	10.1128/JCM.00772-09