Tolterodine extended release is well tolerated in older subjects

Tolterodine extended release is well tolerated in older subjects

Summary Objectives:  To investigate the tolerability of tolterodine extended release (ER) in older subjects with overactive bladder (OAB). Methods:  This was a retrospective analysis of pooled data from five large, randomised, double‐blind, placebo‐controlled trials. Subjects with OAB symptoms, incl...

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Veröffentlicht in:International journal of clinical practice (Esher) 2009-08, Vol.63 (8), p.1198-1204
Hauptverfasser: Griebling, T. L., Kraus, S. R., Richter, H. E., Glasser, D. B., Carlsson, M.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Benzhydryl Compounds - administration & dosage
Benzhydryl Compounds - adverse effects
Biological and medical sciences
Bladder
Clinical trials
Cresols - administration & dosage
Cresols - adverse effects
Delayed-Action Preparations
Drug therapy
Female
General aspects
Humans
Male
Medical disorders
Medical sciences
Middle Aged
Muscarinic Antagonists - administration & dosage
Muscarinic Antagonists - adverse effects
Older people
Phenylpropanolamine - administration & dosage
Phenylpropanolamine - adverse effects
Randomized Controlled Trials as Topic
Retrospective Studies
Side effects
Tolterodine Tartrate
Treatment Outcome
Urinary Bladder, Overactive - drug therapy
Urology
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Beschreibung
Zusammenfassung:Summary Objectives:  To investigate the tolerability of tolterodine extended release (ER) in older subjects with overactive bladder (OAB). Methods:  This was a retrospective analysis of pooled data from five large, randomised, double‐blind, placebo‐controlled trials. Subjects with OAB symptoms, including urinary frequency and urgency (and nocturia in two studies) with or without urgency urinary incontinence, received qd treatment with tolterodine ER (4 mg) or placebo for 8–12 weeks. Data were stratified post hoc by age group:
ISSN:1368-5031
1742-1241
DOI:10.1111/j.1742-1241.2009.02108.x