Chronic Kidney Disease Associated Mortality in Diastolic Versus Systolic Heart Failure: A Propensity Matched Study

Chronic kidney disease (CKD) is common and is associated with increased mortality in heart failure (HF). However, it is unknown whether the effect of CKD on mortality varies by left ventricular ejection fraction (LVEF). We evaluated the effect of CKD on mortality in patients with systolic (LVEF ≤45%...

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Veröffentlicht in:	The American journal of cardiology 2007-02, Vol.99 (3), p.393-398
Hauptverfasser:	Ahmed, Ali, MD, MPH, Rich, Michael W., MD, Sanders, Paul W., MD, Perry, Gilbert J., MD, Bakris, George L., MD, Zile, Michael R., MD, Love, Thomas E., PhD, Aban, Inmaculada B., PhD, Shlipak, Michael G., MD, MPH
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Cardiology. Vascular system Cardiotonic Agents - therapeutic use Cardiovascular Chronic illnesses Confidence Intervals Correlation analysis Diastole Digitalis Glycosides - therapeutic use Disease Progression Female Follow-Up Studies Glomerular Filtration Rate Heart Heart failure Heart Failure - complications Heart Failure - drug therapy Heart Failure - mortality Heart failure, cardiogenic pulmonary edema, cardiac enlargement Humans Kidney diseases Kidney Failure, Chronic - complications Kidney Failure, Chronic - physiopathology Kidneys Male Medical sciences Middle Aged Mortality Myocardial Contraction - physiology Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Prognosis Proportional Hazards Models Renal failure Retrospective Studies Risk Factors Survival Rate - trends Systole Urinary system involvement in other diseases. Miscellaneous
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Zusammenfassung:	Chronic kidney disease (CKD) is common and is associated with increased mortality in heart failure (HF). However, it is unknown whether the effect of CKD on mortality varies by left ventricular ejection fraction (LVEF). We evaluated the effect of CKD on mortality in patients with systolic (LVEF ≤45%) and diastolic (LVEF >45%) HF. Of the 7,788 patients in the Digitalis Investigation Group trial, 3,527 (45%) had CKD (estimated glomerular filtration rate
ISSN:	0002-9149 1879-1913
DOI:	10.1016/j.amjcard.2006.08.042