(−)-Epigallocatechin-3-gallate Is a Novel Hsp90 Inhibitor

(−)-Epigallocatechin-3-gallate (EGCG), a major component of green tea, protects against certain types of cancers, although the mechanism has not yet been determined. It was previously demonstrated that EGCG blocks aryl hydrocarbon receptor (AhR)-mediated transcription induced by the potent carcinoge...

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Veröffentlicht in:Biochemistry (Easton) 2009-01, Vol.48 (2), p.336-345
Hauptverfasser: Yin, Zhengyu, Henry, Ellen C, Gasiewicz, Thomas A
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Sprache:eng
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