Fluctuation AnaLysis CalculatOR: a web tool for the determination of mutation rate using Luria–Delbrück fluctuation analysis

The program Fluctuation AnaLysis CalculatOR (FALCOR) is a web tool designed for use with Luria–Delbrück fluctuation analysis to calculate the frequency and rate from various mutation assays in bacteria and yeast. Three calculation methods are available through this program: (i) Ma-Sandri-Sarkar Maxi...

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Veröffentlicht in:	Bioinformatics 2009-06, Vol.25 (12), p.1564-1565
Hauptverfasser:	Hall, Brandon M., Ma, Chang-Xing, Liang, Ping, Singh, Keshav K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Applications Note Biological and medical sciences Computational Biology - methods Databases, Genetic Fundamental and applied biological sciences. Psychology General aspects Internet Likelihood Functions Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) Mutation - genetics Software
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Beschreibung
Zusammenfassung:	The program Fluctuation AnaLysis CalculatOR (FALCOR) is a web tool designed for use with Luria–Delbrück fluctuation analysis to calculate the frequency and rate from various mutation assays in bacteria and yeast. Three calculation methods are available through this program: (i) Ma-Sandri-Sarkar Maximum Likelihood Estimator (MSS-MLE) method, (ii) Lea-Coulson method of the median (LC) and (iii) frequency. Availability: The FALCOR rate calculator is currently accessible at http://www.mitochondria.org/protocols/FALCOR.html. This program is written as a Java™ Applet, requiring a web browser enabled with Sun MicroSystems' Java Virtual Machine. Contact: brandon.hall@roswellpark.org
ISSN:	1367-4803 1460-2059 1367-4811
DOI:	10.1093/bioinformatics/btp253