Antibiotic Resistance Patterns in Invasive Group B Streptococcal Isolates

Antibiotics are used for both group B streptococcal (GBS) prevention and treatment. Active population-based surveillance for invasive GBS disease was conducted in four states during 1996–2003. Of 3813 case-isolates, 91.0% (3471) were serotyped, 77.1% (2937) had susceptibility testing, and 46.6% (347...

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Veröffentlicht in:	Infectious Diseases in Obstetrics and Gynecology 2008, Vol.2008 (2008), p.72-76
Hauptverfasser:	Whitney, Cynthia G., Castor, Mei L., Como-Sabetti, Kathryn, Facklam, Richard R., Ferrieri, Patricia, Bartkus, Joanne M., Juni, Billie A., Cieslak, Paul R., Farley, Monica M., Dumas, Nellie B., Schrag, Stephanie J., Lynfield, Ruth
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Colony Count, Microbial Dose-Response Relationship, Drug Drug Resistance, Bacterial Humans Microbial Sensitivity Tests Prevalence Public Health Serotyping Streptococcal Infections - drug therapy Streptococcus agalactiae - classification Streptococcus agalactiae - drug effects
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Zusammenfassung:	Antibiotics are used for both group B streptococcal (GBS) prevention and treatment. Active population-based surveillance for invasive GBS disease was conducted in four states during 1996–2003. Of 3813 case-isolates, 91.0% (3471) were serotyped, 77.1% (2937) had susceptibility testing, and 46.6% (3471) had both. All were sensitive to penicillin, ampicillin, cefazolin, cefotaxime, and vancomycin. Clindamycin and erythromycin resistance was 12.7% and 25.6%, respectively, and associated with serotype V (P
ISSN:	1064-7449 1098-0997
DOI:	10.1155/2008/727505