Aetiology, diagnosis, and management of hypopituitarism in adult life

Hypopituitarism is a complex medical condition associated with increased morbidity and mortality, requires complicated treatment regimens, and necessitates lifelong follow up by the endocrinologist. The causes, clinical features, and the management of hypopituitarism including endocrine replacement...

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Veröffentlicht in:	Postgraduate medical journal 2006-04, Vol.82 (966), p.259-266
Hauptverfasser:	Prabhakar, V K B, Shalet, S M
Format:	Artikel
Sprache:	eng
Schlagworte:	ACTH adrenocorticotrophic hormone Adrenocorticotropic Hormone - deficiency Adult adult growth hormone deficiency AGHD Biological and medical sciences BMD bone mineral density cerebrospinal fluid CSF diabetes insipidus endocrine replacement therapy Endocrinopathies Female follicle stimulating hormone FSH General aspects GHD GHRH glucagon stimulation test GnRH gonadotrophin releasing hormone Gonadotropins - deficiency growth hormone growth hormone deficiency growth hormone releasing hormone GST HCG hormone replacement therapy Hormone Replacement Therapy - methods HPA HRT human chorionic gonadotrophin Human Growth Hormone - deficiency Humans hydrocortisone hypopituitarism Hypopituitarism - diagnosis Hypopituitarism - drug therapy Hypopituitarism - etiology hypothalamic-pituitary-adrenal Hypothalamus. Hypophysis. Epiphysis (diseases) IGF1 insulin tolerance test insulin-like growth factor 1 ITT luteinising hormone magnetic resonance Male Medical sciences MPHD multiple pituitary hormone deficiencies NFPA Non tumoral diseases. Target tissue resistance. Benign neoplasms non-functioning pituitary adenoma pituitary hormone replacement therapy PRL prolactin prostate specific antigen PSA QoL quality of life Review SMR standardised mortality ratio thyroid stimulating hormone thyrotrophin releasing hormone TRH TSH
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Beschreibung
Zusammenfassung:	Hypopituitarism is a complex medical condition associated with increased morbidity and mortality, requires complicated treatment regimens, and necessitates lifelong follow up by the endocrinologist. The causes, clinical features, and the management of hypopituitarism including endocrine replacement therapy are considered in this review article.
ISSN:	0032-5473 1469-0756
DOI:	10.1136/pgmj.2005.039768