miRNA Editing—We Should Have Inosine This Coming

miRNA Editing—We Should Have Inosine This Coming

In a recent issue of Science, Nishikura and colleagues provide the first evidence that editing of a microRNA (miRNA) precursor by ADARs can modulate the target specificity of the mature miRNA ( Kawahara et al., 2007).

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Bibliographische Detailangaben
Veröffentlicht in:Molecular cell 2007-03, Vol.25 (6), p.792-793
Hauptverfasser: Habig, Jeffrey W., Dale, Taraka, Bass, Brenda L.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Humans
Inosine - metabolism
Introns
MicroRNAs - genetics
RNA Editing - genetics
RNA Interference
RNA, Double-Stranded - metabolism
RNA, Small Interfering - genetics
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Beschreibung
Zusammenfassung:In a recent issue of Science, Nishikura and colleagues provide the first evidence that editing of a microRNA (miRNA) precursor by ADARs can modulate the target specificity of the mature miRNA ( Kawahara et al., 2007).
ISSN:1097-2765
1097-4164
DOI:10.1016/j.molcel.2007.03.010