Time microscopy for all kinds of data including circadian clock biology

Data showing a rhythm to the naked eye prominently, barely or not at all were described as kinds A, B and C, respectively. Here, we document good agreement between estimates of maxima and minima with eyeballing and with the addition of point and interval estimates of parameters in kind A data. We al...

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Veröffentlicht in:Biomedicine & pharmacotherapy 2005-10, Vol.59 (Suppl 1), p.S20-S23
Hauptverfasser: Katinas, G.S., Halberg, F., Cornélissen, G., Otsuka, K., Bakken, E.E.
Format: Artikel
Sprache:eng
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Zusammenfassung:Data showing a rhythm to the naked eye prominently, barely or not at all were described as kinds A, B and C, respectively. Here, we document good agreement between estimates of maxima and minima with eyeballing and with the addition of point and interval estimates of parameters in kind A data. We also construct a chart that provides estimates of uncertainties that can be obtained objectively while they are more difficult to quantify subjectively; again there is agreement. Interval as point estimates of rhythm characteristics and parameter comparisons are useful in charting all kinds of data and become indispensable as we proceed from kind A to kind C data. Illustrations included herein from molecular biology apply equally to all aspects of transdisciplinary science.
ISSN:0753-3322
1950-6007
DOI:10.1016/S0753-3322(05)80005-8