Incidence and predictors of delayed chronic kidney disease in long‐term survivors of hematopoietic cell transplantation

BACKGROUND. The authors investigated the risk of delayed chronic kidney disease (CKD) in 1190 adult hematopoietic cell transplantation (HCT) survivors who underwent HCT for hematologic malignancies or aplastic anemia between 1976 and 1997 and survived for at least 1 year. METHODS. CKD was defined as...

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Veröffentlicht in:	Cancer 2008-10, Vol.113 (7), p.1580-1587
Hauptverfasser:	Choi, Michael, Sun, Can‐Lan, Kurian, Seira, Carter, Andrea, Francisco, Liton, Forman, Stephen J, Bhatia, Smita
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Anemia, Aplastic - therapy Biological and medical sciences calcineurin inhibitors Chronic Disease Cohort Studies cyclosporine A Female graft‐versus‐host disease Hematologic Neoplasms - therapy hematopoietic cell transplantation Hematopoietic Stem Cell Transplantation - adverse effects Humans Incidence Kidney Diseases - epidemiology Kidney Diseases - etiology Kidneys Male Medical sciences Middle Aged Nephrology. Urinary tract diseases nephrotoxicity primary multiple myeloma Retrospective Studies Risk Survivors tacrolimus Transplantation, Autologous Transplantation, Homologous Tumors Urinary system involvement in other diseases. Miscellaneous
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Zusammenfassung:	BACKGROUND. The authors investigated the risk of delayed chronic kidney disease (CKD) in 1190 adult hematopoietic cell transplantation (HCT) survivors who underwent HCT for hematologic malignancies or aplastic anemia between 1976 and 1997 and survived for at least 1 year. METHODS. CKD was defined as a sustained elevation of serum creatinine that indicated a glomerular filtration rate of
ISSN:	0008-543X 1097-0142
DOI:	10.1002/cncr.23773