Subunit Mobility and the Chaperone Activity of Recombinant αB-Crystallin

Subunit Mobility and the Chaperone Activity of Recombinant αB-Crystallin

The comparison of the chaperone-like activity of native and covalently cross-linked human αB-crystallins has confirmed the important role of the subunit mobility in the chaperoning mechanism. Our data clearly demonstrate that the chaperone-like activity of α-crystallin is not only a surface phenomen...

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Veröffentlicht in:The open biochemistry journal 2008-09, Vol.2, p.116-120
Hauptverfasser: Krushelnitsky, A, Mukhametshina, N, Gogolev, Y, Tarasova, N, Faizullin, D, Zinkevich, T, Gnezdilov, O, Fedotov, V
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Sprache:eng
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Zusammenfassung:The comparison of the chaperone-like activity of native and covalently cross-linked human αB-crystallins has confirmed the important role of the subunit mobility in the chaperoning mechanism. Our data clearly demonstrate that the chaperone-like activity of α-crystallin is not only a surface phenomenon as was suggested by some researchers.
ISSN:1874-091X
DOI:10.2174/1874091X00802010116