The Dielectric Response of Spherical Live Cells in Suspension: An Analytic Solution

We develop a theoretical framework to describe the dielectric response of live cells in suspensions when placed in low external electric fields. The treatment takes into account the presence of the cell's membrane and of the charge movement at the membrane's surfaces. For spherical cells s...

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Veröffentlicht in:Biophysical journal 2008-11, Vol.95 (9), p.4174-4182
Hauptverfasser: Prodan, Emil, Prodan, Camelia, Miller, John H.
Format: Artikel
Sprache:eng
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Zusammenfassung:We develop a theoretical framework to describe the dielectric response of live cells in suspensions when placed in low external electric fields. The treatment takes into account the presence of the cell's membrane and of the charge movement at the membrane's surfaces. For spherical cells suspended in aqueous solutions, we give an analytic solution for the dielectric function, which is shown to account for the α- and β-plateaus seen in many experimental data. The effect of different physical parameters on the dielectric curves is methodically analyzed.
ISSN:0006-3495
1542-0086
DOI:10.1529/biophysj.108.137042