Headache in Children with Sickle Cell Disease: Prevalence and Associated Factors

Objective To compare the prevalence of frequent headache in children with sickle cell disease (SCD) to that of black control subjects and to assess factors associated with headache in SCD. Study design In this cross-sectional study, a headache questionnaire was administered to subjects with SCD and...

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Veröffentlicht in:	The Journal of pediatrics 2007-07, Vol.151 (1), p.67-72.e1
Hauptverfasser:	Niebanck, Alison E., MD, Pollock, Avrum N., MD, Smith-Whitley, Kim, MD, Raffini, Leslie J., MD, Zimmerman, Robert A., MD, Ohene-Frempong, Kwaku, MD, Kwiatkowski, Janet L., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Age Distribution Analysis of Variance Anemia, Sickle Cell - diagnosis Anemia, Sickle Cell - epidemiology Anemias. Hemoglobinopathies Biological and medical sciences Case-Control Studies Child Child, Preschool Comorbidity Cross-Sectional Studies Diseases of red blood cells Female General aspects Headache - diagnosis Headache - epidemiology Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Hematologic and hematopoietic diseases Humans Male Medical sciences Migraine Disorders - diagnosis Migraine Disorders - epidemiology Nervous system (semeiology, syndromes) Neurology Pain Measurement Pediatrics Prevalence Probability Prognosis Reference Values Risk Assessment Severity of Illness Index Sex Distribution
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Zusammenfassung:	Objective To compare the prevalence of frequent headache in children with sickle cell disease (SCD) to that of black control subjects and to assess factors associated with headache in SCD. Study design In this cross-sectional study, a headache questionnaire was administered to subjects with SCD and black control subjects. Subjects answered supplementary questions about SCD complications. Clinical and radiographic information were abstracted from medical charts for subjects with SCD. Results Children (n = 241) with SCD and 141 control subjects were studied; 32.4% (95% CI 26.5%-38.7%) of subjects with SCD reported having headaches at least weekly, similar to control subjects at 27% (95% CI 19.8%-35.1%, P = NS); however, in children
ISSN:	0022-3476 1097-6833
DOI:	10.1016/j.jpeds.2007.02.015