Enantioselective Total Synthesis of (+)-Gliocladin C
The first total synthesis of gliocladin C, a fungal-derived marine alkaloid containing a rare trioxopiperazine fragment, is reported. This asymmetric synthesis establishes the absolute configuration of this structurally novel natural product.
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| Veröffentlicht in: | Organic letters 2007-01, Vol.9 (2), p.339-341 |
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| container_end_page | 341 |
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| container_issue | 2 |
| container_start_page | 339 |
| container_title | Organic letters |
| container_volume | 9 |
| creator | Overman, Larry E Shin, Youseung |
| description | The first total synthesis of gliocladin C, a fungal-derived marine alkaloid containing a rare trioxopiperazine fragment, is reported. This asymmetric synthesis establishes the absolute configuration of this structurally novel natural product. |
| doi_str_mv | 10.1021/ol062801y |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1523-7060 |
| ispartof | Organic letters, 2007-01, Vol.9 (2), p.339-341 |
| issn | 1523-7060 1523-7052 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2526118 |
| source | ACS Publications; MEDLINE |
| subjects | Alkaloids - chemical synthesis Alkaloids - chemistry Biological Products - chemical synthesis Biological Products - chemistry Molecular Conformation Piperazines - chemical synthesis Piperazines - chemistry Pyrrolidinones - chemical synthesis Pyrrolidinones - chemistry Stereoisomerism |
| title | Enantioselective Total Synthesis of (+)-Gliocladin C |
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