MASIC: A software program for fast quantitation and flexible visualization of chromatographic profiles from detected LC–MS(/MS) features

MASIC: A software program for fast quantitation and flexible visualization of chromatographic profiles from detected LC–MS(/MS) features

Quantitative analysis of liquid chromatography (LC)–mass spectrometry (MS) and tandem mass spectrometry (MS/MS) data is essential to many proteomics studies. We have developed MASIC 2 2 Availability: MASIC may be downloaded free of charge at http://www.ncrr.pnl.gov/software/. to accurately measure p...

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Veröffentlicht in:Computational Biology and Chemistry, 32(3):215-217 32(3):215-217, 2008-06, Vol.32 (3), p.215-217
Hauptverfasser: Monroe, Matthew E., Shaw, Jason L., Daly, Don S., Adkins, Joshua N., Smith, Richard D.
Format: Artikel
Sprache:eng
Schlagworte:
Algorithms
Chromatography, Liquid - methods
Computer Simulation
Liquid chromatography–tandem mass spectrometry (LC–MS/MS)
Mass Spectrometry - methods
Peptides - chemistry
Proteomics
Quantification
Quantitation
Selected ion chromatogram
Software
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Beschreibung
Zusammenfassung:Quantitative analysis of liquid chromatography (LC)–mass spectrometry (MS) and tandem mass spectrometry (MS/MS) data is essential to many proteomics studies. We have developed MASIC 2 2 Availability: MASIC may be downloaded free of charge at http://www.ncrr.pnl.gov/software/. to accurately measure peptide abundances and LC elution times in LC–MS/MS analyses. This software program uses an efficient processing algorithm to quickly generate mass specific selected ion chromatograms from a dataset and provides an interactive browser that allows users to examine individual chromatograms with a variety of options.
ISSN:1476-9271
1476-928X
DOI:10.1016/j.compbiolchem.2008.02.006