Microtubule Release from the Centrosome

Although microtubules (MTs) are generally thought to originate at the centrosome, a number of cell types have significant populations of MTs with no apparent centrosomal connection. The origin of these noncentrosomal MTs has been unclear. We applied kinetic analysis of MT formation in vivo to establ...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1997-05, Vol.94 (10), p.5078-5083
Hauptverfasser:	Keating, T. J., Peloquin, J. G., Rodionov, V. I., Momcilovic, D., Borisy, G. G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal cells Animals Biological Sciences Cell Line Cells Cellular biology Centrosome - physiology Centrosome - ultrastructure Centrosomes Depolymerization Dipodomys Epithelial cells Epithelium Interphase Kidney Kinetics Lasers Microtubules Microtubules - physiology Microtubules - ultrastructure Movement Neurons Nucleation Time Factors Tubulin - isolation & purification Tubulin - physiology
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