Synthesis of gemcitabine triphosphate (dFdCTP) as a tris(triethylammonium) salt

First synthesis of gemcitabine triphosphate (dFdCTP) as a tris(triethylammonium) salt is reported. First synthesis of gemcitabine triphosphate (dFdCTP) as a tris(triethylammonium) salt is reported.

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Veröffentlicht in:	Bioorganic & medicinal chemistry 2008-05, Vol.18 (9), p.2957-2958
Hauptverfasser:	Risbood, Prabhakar A., Kane, Charles T., Hossain, Md. Tafazzal, Vadapalli, Sudhakarrao, Chadda, Satish K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antimetabolites, Antineoplastic - chemical synthesis Antimetabolites, Antineoplastic - pharmacology Antineoplastic agents Biological and medical sciences Chromatography, High Pressure Liquid Chromatography, Thin Layer Deoxycytidine - analogs & derivatives Deoxycytidine - chemical synthesis Deoxycytidine - pharmacology Gemcitabine Gemcitabine triphosphate (dFdCTP) General aspects Humans Medical sciences Models, Chemical Pharmacology. Drug treatments Polyphosphates - chemical synthesis Polyphosphates - pharmacology Quaternary Ammonium Compounds - chemistry Quaternary Ammonium Compounds - pharmacology Salts - chemistry Salts - pharmacology Tromethamine - chemistry Tromethamine - pharmacology Tumor Cells, Cultured - drug effects
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Beschreibung
Zusammenfassung:	First synthesis of gemcitabine triphosphate (dFdCTP) as a tris(triethylammonium) salt is reported. First synthesis of gemcitabine triphosphate (dFdCTP) as a tris(triethylammonium) salt is reported.
ISSN:	0960-894X 0968-0896 1464-3405 1464-3405 1464-3391
DOI:	10.1016/j.bmcl.2008.03.063