Propranolol in acute intermittent porphyria

Propranolol in acute intermittent porphyria

Twenty cases of acute intermittent porphyria were studied during the acute phase. Cardiovascular manifestations were noted in all the cases, with tachycardia in 20 and with hypertension in 17. Propranolol in doses ranging from 20--200 mg was given to all the cases and produced adequate control of ta...

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Veröffentlicht in:Postgraduate medical journal 1979-08, Vol.55 (646), p.546-547
Hauptverfasser: Menawat, A. S., Panwar, R. B., Kochar, D. K., Joshi, C. K.
Format: Artikel
Sprache:eng
Schlagworte:
Acute Disease
Blood Pressure - drug effects
Drug Administration Schedule
Heart Rate - drug effects
Humans
Porphyrias - drug therapy
Porphyrias - physiopathology
Propranolol - administration & dosage
Propranolol - therapeutic use
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Zusammenfassung:Twenty cases of acute intermittent porphyria were studied during the acute phase. Cardiovascular manifestations were noted in all the cases, with tachycardia in 20 and with hypertension in 17. Propranolol in doses ranging from 20--200 mg was given to all the cases and produced adequate control of tachycardia and hypertension. At follow-up, smaller doses of propranolol were found to maintain the pulse rate and BP within normal limits and also to prevent acute attacks.
ISSN:0032-5473
1469-0756
DOI:10.1136/pgmj.55.646.546