Association of Addison's disease with autoimmune disorders--a long-term observation of 180 patients

This study aimed at evaluating the frequency of autoimmune disorders in Addison's disease. We have observed 180 patients (113 females, 67 males, aged 9-74 years) for 1 to 26 years. Tuberculosis was noted in 54 patients. Autoimmune disorders were found in 80 patients (44%); however, 125 (69%) pa...

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Veröffentlicht in:	Postgraduate medical journal 1991-11, Vol.67 (793), p.984-987
Hauptverfasser:	Kasperlik-Zaluska, A. A., Migdalska, B., Czarnocka, B., Drac-Kaniewska, J., Niegowska, E., Czech, W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Addison Disease - complications Adolescent Adult Aged Autoimmune Diseases - complications Autoimmune Diseases - epidemiology Biological and medical sciences Child Endocrinopathies Female Follow-Up Studies Humans Male Medical sciences Middle Aged Prevalence Sex Factors Thyrotoxicosis - complications Tuberculosis - complications
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Zusammenfassung:	This study aimed at evaluating the frequency of autoimmune disorders in Addison's disease. We have observed 180 patients (113 females, 67 males, aged 9-74 years) for 1 to 26 years. Tuberculosis was noted in 54 patients. Autoimmune disorders were found in 80 patients (44%); however, 125 (69%) patients were believed to have an autoimmune origin of adrenocortical insufficiency. In 20 patients two or more autoimmune disorders were found to coexist with Addison's disease.
ISSN:	0032-5473 1469-0756
DOI:	10.1136/pgmj.67.793.984