The relationship between T-lymphocyte infiltration, stage, tumour grade and survival in patients undergoing curative surgery for renal cell cancer
The present study examined the relationship between tumour stage, grade, T-lymphocyte subset infiltration and survival in patients who had undergone potentially curative surgery for renal clear-cell cancer ( n =73). Intratumoural CD4+ T-lymphocyte infiltrate was associated with poor cancer-specific...
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| Veröffentlicht in: | British journal of cancer 2003-11, Vol.89 (10), p.1906-1908 |
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| container_issue | 10 |
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| container_title | British journal of cancer |
| container_volume | 89 |
| creator | Bromwich, E J McArdle, P A Canna, K McMillan, D C McNicol, A-M Brown, M Aitchison, M |
| description | The present study examined the relationship between tumour stage, grade, T-lymphocyte subset infiltration and survival in patients who had undergone potentially curative surgery for renal clear-cell cancer (
n
=73). Intratumoural CD4+ T-lymphocyte infiltrate was associated with poor cancer-specific survival, independent of grade, in this cohort. |
| doi_str_mv | 10.1038/sj.bjc.6601400 |
| format | Article |
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Intratumoural CD4+ T-lymphocyte infiltrate was associated with poor cancer-specific survival, independent of grade, in this cohort.</description><subject>Aged</subject><subject>Antigens</subject><subject>Biological and medical sciences</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Cancer Research</subject><subject>Carcinoma, Renal Cell - immunology</subject><subject>Carcinoma, Renal Cell - pathology</subject><subject>Carcinoma, Renal Cell - surgery</subject><subject>Cohort Studies</subject><subject>Drug Resistance</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>Kidney cancer</subject><subject>Kidney Neoplasms - immunology</subject><subject>Kidney Neoplasms - pathology</subject><subject>Kidney Neoplasms - surgery</subject><subject>Kidneys</subject><subject>Lymphocytes</subject><subject>Male</subject><subject>Medical research</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Molecular Medicine</subject><subject>molecular-and-cellular-pathology</subject><subject>Neoplasm Staging</subject><subject>Nephrology. Urinary tract diseases</subject><subject>Oncology</subject><subject>Patients</subject><subject>Pilot projects</subject><subject>Short Communication</subject><subject>Surgery</subject><subject>Survival Analysis</subject><subject>T-Lymphocytes - immunology</subject><subject>Treatment Outcome</subject><subject>Tumors</subject><subject>Tumors of the urinary system</subject><issn>0007-0920</issn><issn>1532-1827</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kV2L1DAUhoMo7rh666UEQa-2s0nTj-RmQRa_YMGb8TqkyWknpU3GpB2Zv-EvNnWKo4I3CeE8ec97zovQS0q2lDB-G_tt0-ttVRFaEPIIbWjJ8ozyvH6MNoSQOiMiJ1foWYx9egrC66foihYVzQWhG_RjtwccYFCT9S7u7QE3MH0HcHiXDafxsPf6NAG2rrXDFH5RNzhOqoMbPM2jnwPugjKAlTM4zuFoj2pIOD4kFtwU8ewMhM5b12E9LwpHWMAOwgm3PqTmLv3QMKRDOQ3hOXrSqiHCi_W-Rl8_vN_df8oevnz8fP_uIdMFZ1OWt1ByDbylhpWFASqEaaCuaaErzg01uSoFZYIXptZlS4Fpo3jbUAairJVm1-jurHuYmxGMTm6DGuQh2FGFk_TKyr8rzu5l548yZ6IoWJkE3q4CwX-bIU5ytHEZRDnwc5Q1ZUUtWJXA1_-AfVpcGjsmLUJozkueoO0Z0sHHGKD97YQSuWQtYy9T1nLNOn149af_C76Gm4A3K6CiVkMb0nptvHAlo2k_i9DtmYup5FIwF3v_af0TnI_HTg</recordid><startdate>20031117</startdate><enddate>20031117</enddate><creator>Bromwich, E J</creator><creator>McArdle, P A</creator><creator>Canna, K</creator><creator>McMillan, D C</creator><creator>McNicol, A-M</creator><creator>Brown, M</creator><creator>Aitchison, M</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>C6C</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TO</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20031117</creationdate><title>The relationship between T-lymphocyte infiltration, stage, tumour grade and survival in patients undergoing curative surgery for renal cell cancer</title><author>Bromwich, E J ; McArdle, P A ; Canna, K ; McMillan, D C ; McNicol, A-M ; Brown, M ; Aitchison, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c483t-2fe58ce8f1d354de199dbe7714c688d1d2a5913984d7c5f1e3cda8fb13e957ac3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Aged</topic><topic>Antigens</topic><topic>Biological and medical sciences</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Cancer Research</topic><topic>Carcinoma, Renal Cell - immunology</topic><topic>Carcinoma, Renal Cell - pathology</topic><topic>Carcinoma, Renal Cell - surgery</topic><topic>Cohort Studies</topic><topic>Drug Resistance</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>Kidney cancer</topic><topic>Kidney Neoplasms - immunology</topic><topic>Kidney Neoplasms - pathology</topic><topic>Kidney Neoplasms - surgery</topic><topic>Kidneys</topic><topic>Lymphocytes</topic><topic>Male</topic><topic>Medical research</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Molecular Medicine</topic><topic>molecular-and-cellular-pathology</topic><topic>Neoplasm Staging</topic><topic>Nephrology. Urinary tract diseases</topic><topic>Oncology</topic><topic>Patients</topic><topic>Pilot projects</topic><topic>Short Communication</topic><topic>Surgery</topic><topic>Survival Analysis</topic><topic>T-Lymphocytes - immunology</topic><topic>Treatment Outcome</topic><topic>Tumors</topic><topic>Tumors of the urinary system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bromwich, E J</creatorcontrib><creatorcontrib>McArdle, P A</creatorcontrib><creatorcontrib>Canna, K</creatorcontrib><creatorcontrib>McMillan, D C</creatorcontrib><creatorcontrib>McNicol, A-M</creatorcontrib><creatorcontrib>Brown, M</creatorcontrib><creatorcontrib>Aitchison, M</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>British journal of cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bromwich, E J</au><au>McArdle, P A</au><au>Canna, K</au><au>McMillan, D C</au><au>McNicol, A-M</au><au>Brown, M</au><au>Aitchison, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The relationship between T-lymphocyte infiltration, stage, tumour grade and survival in patients undergoing curative surgery for renal cell cancer</atitle><jtitle>British journal of cancer</jtitle><stitle>Br J Cancer</stitle><addtitle>Br J Cancer</addtitle><date>2003-11-17</date><risdate>2003</risdate><volume>89</volume><issue>10</issue><spage>1906</spage><epage>1908</epage><pages>1906-1908</pages><issn>0007-0920</issn><eissn>1532-1827</eissn><coden>BJCAAI</coden><abstract>The present study examined the relationship between tumour stage, grade, T-lymphocyte subset infiltration and survival in patients who had undergone potentially curative surgery for renal clear-cell cancer (
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| fulltext | fulltext |
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| source | MEDLINE; Springer Nature - Complete Springer Journals; Nature Journals Online; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Aged Antigens Biological and medical sciences Biomedical and Life Sciences Biomedicine Cancer Research Carcinoma, Renal Cell - immunology Carcinoma, Renal Cell - pathology Carcinoma, Renal Cell - surgery Cohort Studies Drug Resistance Epidemiology Female Humans Immunohistochemistry Kidney cancer Kidney Neoplasms - immunology Kidney Neoplasms - pathology Kidney Neoplasms - surgery Kidneys Lymphocytes Male Medical research Medical sciences Middle Aged Molecular Medicine molecular-and-cellular-pathology Neoplasm Staging Nephrology. Urinary tract diseases Oncology Patients Pilot projects Short Communication Surgery Survival Analysis T-Lymphocytes - immunology Treatment Outcome Tumors Tumors of the urinary system |
| title | The relationship between T-lymphocyte infiltration, stage, tumour grade and survival in patients undergoing curative surgery for renal cell cancer |
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