The relationship between T-lymphocyte infiltration, stage, tumour grade and survival in patients undergoing curative surgery for renal cell cancer

The present study examined the relationship between tumour stage, grade, T-lymphocyte subset infiltration and survival in patients who had undergone potentially curative surgery for renal clear-cell cancer ( n =73). Intratumoural CD4+ T-lymphocyte infiltrate was associated with poor cancer-specific...

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Veröffentlicht in:	British journal of cancer 2003-11, Vol.89 (10), p.1906-1908
Hauptverfasser:	Bromwich, E J, McArdle, P A, Canna, K, McMillan, D C, McNicol, A-M, Brown, M, Aitchison, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antigens Biological and medical sciences Biomedical and Life Sciences Biomedicine Cancer Research Carcinoma, Renal Cell - immunology Carcinoma, Renal Cell - pathology Carcinoma, Renal Cell - surgery Cohort Studies Drug Resistance Epidemiology Female Humans Immunohistochemistry Kidney cancer Kidney Neoplasms - immunology Kidney Neoplasms - pathology Kidney Neoplasms - surgery Kidneys Lymphocytes Male Medical research Medical sciences Middle Aged Molecular Medicine molecular-and-cellular-pathology Neoplasm Staging Nephrology. Urinary tract diseases Oncology Patients Pilot projects Short Communication Surgery Survival Analysis T-Lymphocytes - immunology Treatment Outcome Tumors Tumors of the urinary system
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Zusammenfassung:	The present study examined the relationship between tumour stage, grade, T-lymphocyte subset infiltration and survival in patients who had undergone potentially curative surgery for renal clear-cell cancer ( n =73). Intratumoural CD4+ T-lymphocyte infiltrate was associated with poor cancer-specific survival, independent of grade, in this cohort.
ISSN:	0007-0920 1532-1827
DOI:	10.1038/sj.bjc.6601400