New molecular pathways in angiogenesis
Angiogenesis has developed into a major area of cancer research. Recently, several newly identified signalling pathways have been shown to play a role in both normal and pathological (including tumour) angiogenesis. Several of the molecules involved in these pathways have potential as novel anti-can...
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| Veröffentlicht in: | British journal of cancer 2003-07, Vol.89 (2), p.228-231 |
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| container_title | British journal of cancer |
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| creator | SUKKUVAB, D. C BICKNELL, Abd R |
| description | Angiogenesis has developed into a major area of cancer research. Recently, several newly identified signalling pathways have been shown to play a role in both normal and pathological (including tumour) angiogenesis. Several of the molecules involved in these pathways have potential as novel anti-cancer therapeutic targets including members of the ephrin/Eph receptor, Notch/delta, sprouty, hedgehog and roundabout/slit families. These developments are reviewed. |
| doi_str_mv | 10.1038/sj.bjc.6601107 |
| format | Article |
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These developments are reviewed.</description><subject>Angiogenesis</subject><subject>Biological and medical sciences</subject><subject>Blood vessels</subject><subject>Cancer research</subject><subject>Endothelium</subject><subject>Ephrins - pharmacology</subject><subject>Hedgehog Proteins</subject><subject>Humans</subject><subject>Hypoxia</subject><subject>Kinases</subject><subject>Ligands</subject><subject>Medical research</subject><subject>Medical sciences</subject><subject>Membrane Proteins - pharmacology</subject><subject>Multiple tumors. Solid tumors. 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| source | MEDLINE; Nature; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Angiogenesis Biological and medical sciences Blood vessels Cancer research Endothelium Ephrins - pharmacology Hedgehog Proteins Humans Hypoxia Kinases Ligands Medical research Medical sciences Membrane Proteins - pharmacology Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Neoplasms - genetics Neoplasms - physiopathology Neovascularization, Pathologic - genetics Receptors, Eph Family - physiology Receptors, Notch Review Signal Transduction Trans-Activators - pharmacology Tumors Vascular endothelial growth factor |
| title | New molecular pathways in angiogenesis |
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