Evaluation of cumulative prognostic scores based on the systemic inflammatory response in patients with inoperable non-small-cell lung cancer

A score based on the combination of the systemic inflammatory response and albumin hazards ratio (HR) 1.70, 95% CI 1.23 – 2.35, P =0.001) was comparable in prognostic value to that based on stage and performance status (HR 1.48, 95% CI 1.12 – 1.95, P =0.006) in patients with inoperable non-small-cel...

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Veröffentlicht in:	British journal of cancer 2003-09, Vol.89 (6), p.1028-1030
Hauptverfasser:	Forrest, L M, McMillan, D C, McArdle, C S, Angerson, W J, Dunlop, D J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - blood Adenocarcinoma - diagnosis Albumins - analysis Biological and medical sciences Biomarkers, Tumor - analysis Biomedical and Life Sciences Biomedicine C-Reactive Protein - analysis Cancer Research Carcinoma, Non-Small-Cell Lung - blood Carcinoma, Non-Small-Cell Lung - diagnosis Carcinoma, Squamous Cell - blood Carcinoma, Squamous Cell - diagnosis Drug Resistance Epidemiology Female Humans Hypoalbuminemia - complications Inflammation Karnofsky Performance Status Lung cancer Lung Neoplasms - blood Lung Neoplasms - diagnosis Male Medical sciences Middle Aged Molecular and Cellular Pathology Molecular Medicine Neoplasm Staging Oncology Pneumology Prognosis Prospective Studies Retrospective Studies Tumors of the respiratory system and mediastinum
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Zusammenfassung:	A score based on the combination of the systemic inflammatory response and albumin hazards ratio (HR) 1.70, 95% CI 1.23 – 2.35, P =0.001) was comparable in prognostic value to that based on stage and performance status (HR 1.48, 95% CI 1.12 – 1.95, P =0.006) in patients with inoperable non-small-cell lung cancer. The former is simple to measure and well standardised.
ISSN:	0007-0920 1532-1827
DOI:	10.1038/sj.bjc.6601242