Effects of Pirimiphos-methyl (An Organophosphate Insecticide) on the Fertility of Adult Male Rats

Organophosphate insecticides represent one of the most widely used classes of pesticides with high potential for human exposure in both rural and residential environments. In the present study, we investigated the effects of pirimiphos-methyl (0, 2-diethylamino-6-methylpirimidin-4-yl O, O-dimethyl p...

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Veröffentlicht in:	African health sciences 2007-03, Vol.7 (1), p.3-9
Hauptverfasser:	Ngoula, Ferdinand, Watcho, Pierre, Dongmo, Marie-Chantal, Kenfack, Augustave, Kamtchouing, Pierre, Tchoumbou, Joseph
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Environmental Exposure - adverse effects Infertility, Male - chemically induced Insecticides - adverse effects Insecticides - blood Male Oligospermia - chemically induced Organothiophosphorus Compounds - adverse effects Organothiophosphorus Compounds - blood Original pirimiphos-methyl, spermatogenesis, fertility, male rats Rats Rats, Wistar Sperm Motility Testis - pathology
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Zusammenfassung:	Organophosphate insecticides represent one of the most widely used classes of pesticides with high potential for human exposure in both rural and residential environments. In the present study, we investigated the effects of pirimiphos-methyl (0, 2-diethylamino-6-methylpirimidin-4-yl O, O-dimethyl phosphorothioate), an organophosphothioate pesticide, on male rat reproductive performances. A total of 24 adult Wistar rats were divided into 4 groups of 6 animals each and orally treated with 0, 41.67, 62.5 or 125 mg/kg of pirimiphos-methyl for 90 days. Results from the study showed a significant increase (p
ISSN:	1680-6905 1729-0503