Mucin Degradation by Bifidobacterium Strains Isolated from the Human Intestinal Microbiota

The presence of the genes engBF (endo-α-N-acetylgalactosaminidase) and afcA (1,2-α-L-fucosidase) was detected in several intestinal Bifidobacterium isolates. Two strains of Bifidobacterium bifidum contained both genes, and they were able to degrade high-molecular weight porcine mucin in vitro. The e...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Applied and Environmental Microbiology 2008-03, Vol.74 (6), p.1936-1940
Hauptverfasser:	Ruas-Madiedo, Patricia, Gueimonde, Miguel, Fernández-García, María, de los Reyes-Gavilán, Clara G, Margolles, Abelardo
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-L-Fucosidase - genetics alpha-L-Fucosidase - metabolism alpha-N-Acetylgalactosaminidase - genetics alpha-N-Acetylgalactosaminidase - metabolism Animals Bacteria Bacterial Proteins - genetics Bacterial Proteins - metabolism Bifidobacterium - classification Bifidobacterium - genetics Bifidobacterium - metabolism Bifidobacterium bifidum Biological and medical sciences Food Microbiology Fundamental and applied biological sciences. Psychology Gene expression Glycoproteins Humans Intestines - microbiology Microbiology Molecular Sequence Data Molecular weight Mucins - metabolism Phylogeny Swine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The presence of the genes engBF (endo-α-N-acetylgalactosaminidase) and afcA (1,2-α-L-fucosidase) was detected in several intestinal Bifidobacterium isolates. Two strains of Bifidobacterium bifidum contained both genes, and they were able to degrade high-molecular weight porcine mucin in vitro. The expression of both genes was highly induced in the presence of mucin.
ISSN:	0099-2240 1098-5336
DOI:	10.1128/AEM.02509-07