Second meiotic arrest and exit in frogs and mice

Mature vertebrate oocytes typically undergo programmed arrest at the second meiotic cell cycle until they are signalled to initiate embryonic development at fertilization. Here, we describe the underlying molecular mechanisms of this second meiotic arrest and release in Xenopus , and compare and con...

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Veröffentlicht in:EMBO reports 2008-03, Vol.9 (3), p.246-251
Hauptverfasser: Perry, Anthony C.F., Verlhac, Marie-Hélène
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creator Perry, Anthony C.F.
Verlhac, Marie-Hélène
description Mature vertebrate oocytes typically undergo programmed arrest at the second meiotic cell cycle until they are signalled to initiate embryonic development at fertilization. Here, we describe the underlying molecular mechanisms of this second meiotic arrest and release in Xenopus , and compare and contrast them with their counterparts in mice.
doi_str_mv 10.1038/embor.2008.22
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source MEDLINE; Wiley Free Archive; Wiley Blackwell Single Titles; PubMed Central; EZB Electronic Journals Library
subjects Animals
Anura
Anura - metabolism
Calcium Signaling
Cell cycle
Cellular biology
cytostatic factor
EMBO06
Embryology
Embryonic growth stage
Emi2
fertilization
Frogs
Homeostasis
Life Sciences
Male
Meiosis
Metaphase
metaphase II
Mice
Review
Rodents
Spermatozoa - cytology
vertebrate meiosis
Vertebrates
Xenopus
title Second meiotic arrest and exit in frogs and mice
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