Second meiotic arrest and exit in frogs and mice

Mature vertebrate oocytes typically undergo programmed arrest at the second meiotic cell cycle until they are signalled to initiate embryonic development at fertilization. Here, we describe the underlying molecular mechanisms of this second meiotic arrest and release in Xenopus , and compare and con...

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Veröffentlicht in:	EMBO reports 2008-03, Vol.9 (3), p.246-251
Hauptverfasser:	Perry, Anthony C.F., Verlhac, Marie-Hélène
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anura Anura - metabolism Calcium Signaling Cell cycle Cellular biology cytostatic factor EMBO06 Embryology Embryonic growth stage Emi2 fertilization Frogs Homeostasis Life Sciences Male Meiosis Metaphase metaphase II Mice Review Rodents Spermatozoa - cytology vertebrate meiosis Vertebrates Xenopus
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Beschreibung
Zusammenfassung:	Mature vertebrate oocytes typically undergo programmed arrest at the second meiotic cell cycle until they are signalled to initiate embryonic development at fertilization. Here, we describe the underlying molecular mechanisms of this second meiotic arrest and release in Xenopus , and compare and contrast them with their counterparts in mice.
ISSN:	1469-221X 1469-3178 1469-221X
DOI:	10.1038/embor.2008.22