A MSC-ing link in metastasis?

Mesenchymal stem cells promote the dissemination of neoplastic cells in a mouse model of breast cancer. The findings sound a cautionary note for anticancer therapies that rely on these cells and provoke a re-evaluation of how metastases form.

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Bibliographische Detailangaben
Veröffentlicht in:	Nature medicine 2007-11, Vol.13 (11), p.1289-1291
Hauptverfasser:	Hurst, Douglas R, Welch, Danny R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Biomedicine Cancer Research Female Infectious Diseases Lymphatic Metastasis - pathology Mammary Neoplasms, Experimental - pathology Melanoma, Experimental - pathology Mesenchymal Stem Cells - pathology Metabolic Diseases Mice Molecular Medicine Neoplasm Metastasis - pathology Neurosciences news-and-views
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Beschreibung
Zusammenfassung:	Mesenchymal stem cells promote the dissemination of neoplastic cells in a mouse model of breast cancer. The findings sound a cautionary note for anticancer therapies that rely on these cells and provoke a re-evaluation of how metastases form.
ISSN:	1078-8956 1546-170X
DOI:	10.1038/nm1107-1289