Immunohistochemical identification of type I procollagen in tumour cells of scirrhous adenocarcinoma of the stomach

Human gastric carcinomas were tested for their immunohistochemical reactivity with anti-type I procollagen antiserum. In all specimens of scirrhous carcinomas, staining of the tumour cells was strongly positive, while in medullary carcinomas staining of the tumour cells was generally poor. These res...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	British journal of cancer 1988-01, Vol.57 (1), p.79-82
Hauptverfasser:	Niitsu, Y, Ito, N, Kohda, K, Owada, M, Morita, K, Sato, S, Watanabe, N, Kohgo, Y, Urushizaki, I
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma, Scirrhous - metabolism Biological and medical sciences Biomedical and Life Sciences Biomedicine Cancer Research Drug Resistance Electrophoresis, Polyacrylamide Gel Epidemiology experimental-oncology Fibroblasts - metabolism Gastroenterology. Liver. Pancreas. Abdomen Humans Immunoenzyme Techniques Medical sciences Molecular Medicine Oncology Procollagen - metabolism Stomach Neoplasms - metabolism Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Human gastric carcinomas were tested for their immunohistochemical reactivity with anti-type I procollagen antiserum. In all specimens of scirrhous carcinomas, staining of the tumour cells was strongly positive, while in medullary carcinomas staining of the tumour cells was generally poor. These results suggest that the tumour cells in scirrhous carcinomas produce collagen in their stroma.
ISSN:	0007-0920 1532-1827
DOI:	10.1038/bjc.1988.13